Adm1n: Created page with "'''A-796,260''' is a drug developed by Abbott Laboratories that acts as a potent and selective cannabinoid CB2 receptor agonist. Replacing the aromatic 3-benzoyl or 3-..."

2015-02-15T11:10:36Z

Created page with "'''A-796,260''' is a drug developed by Abbott Laboratories that acts as a potent and selective cannabinoid CB2 receptor agonist. Replacing the aromatic 3-benzoyl or 3-..."

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'''A-796,260''' is a drug developed by Abbott Laboratories that acts as a potent and selective [[cannabinoid]] [[CB2 receptor]] agonist. Replacing the aromatic 3-benzoyl or 3-naphthoyl group found in most indole derived cannabinoids with the 3-tetramethylcyclopropylmethanone group, imparts significant selectivity for CB2, and A-796,260 was found to be a highly selective CB2 agonist with little affinity for [[CB1]], having a CB2 Ki of 4.6 nM vs 945 nM at CB1.[1] It has potent analgesic and anti-inflammatory actions in animal models, being especially effective in models of neuropathic pain, but without producing [[cannabis]]-like behavioral effects.

==See also==

* [[A-834,735]]
* [[A-836,339]]
* [[JWH-200]]
* [[UR-144]]
* [[XLR-11 (drug)|XLR-11]]

A-796,260 - Revision history

Adm1n: Created page with "'''A-796,260''' is a drug developed by Abbott Laboratories that acts as a potent and selective cannabinoid CB2 receptor agonist. Replacing the aromatic 3-benzoyl or 3-..."