Cannabinol - Revision history

JChidiac at 18:44, 6 May 2015

2015-05-06T18:44:58Z

JChidiac at 03:58, 14 February 2015

2015-02-14T03:58:37Z

Adm1n: Created page with "Cannabinol (CBN) is a weak psychoactive cannabinoid found only in trace amounts in Cannabis sativa and Cannabis indica. It is mostly a metabolite of tetrahyd..."

2015-01-22T06:32:38Z

Created page with "Cannabinol (CBN) is a weak psychoactive cannabinoid found only in trace amounts in Cannabis sativa and Cannabis indica. It is mostly a metabolite of tetrahyd..."

New page

Cannabinol ([[CBN]]) is a weak psychoactive [[cannabinoid]] found only in trace amounts in Cannabis [[sativa]] and Cannabis [[indica]]. It is mostly a metabolite of [[tetrahydrocannabinol]] ([[THC]]). CBN acts as a weak agonist of CB1 receptors but has a higher affinity to CB2 receptors, with lower affinities in comparison to THC. Because it is a somewhat selective CB2 receptor agonist, it is used experimentally as an immunosuppressant.

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 == Medicinal Properties ==
 Because it is a somewhat selective CB2 receptor agonist, it is used experimentally as an immunosuppressant, which can be useful in autoimmune related diseases such as lupus and type 2 diabetes.
-CBN is the cannabinoid with very promising antibacterial properties that may prove useful in treating drug resistant bacterial infections [http://www.ncbi.nlm.nih.gov/pubmed/18681481].
+CBN is the cannabinoid with very promising antibacterial properties that may prove useful in treating drug resistant bacterial infections [http://www.ncbi.nlm.nih.gov/pubmed/18681481]. It has also been implicated as a bone stimulant, and may help regenerate bone mass lost due to osteoporosis [http://www.ncbi.nlm.nih.gov/pubmed/25891514]. Finally, CBN is the primary appetite stimulant in cannabis, and may therefore be used to treat patient under-nutrition caused by nausea.
 It has also been implicated as a bone stimulant, and may help regenerate bone mass lost due to osteoporosis.

← Older revision		Revision as of 03:58, 14 February 2015
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−	Cannabinol ([[CBN]]) is a weak psychoactive [[cannabinoid]] found ~~only~~ in trace amounts in Cannabis [[sativa]] and Cannabis [[indica]]. It is ~~mostly a~~ metabolite of [[tetrahydrocannabinol]] ([[THC]]). CBN acts as a weak agonist of CB1 receptors but has a higher affinity to CB2 receptors, with lower affinities in comparison to THC. Because it is a somewhat selective CB2 receptor agonist, it is used experimentally as an immunosuppressant.	+	Cannabinol ([[CBN]]) is a weak psychoactive [[cannabinoid]] usually found in trace amounts (<1%) in Cannabis [[sativa]] and Cannabis [[indica]]. It is the final metabolite of [[cannabigerolic acid]] ([[CBGa]]) through the [[tetrahydrocannabinol]] ([[THC]]) biosynthetic pathway, and can be indicative of the age of the cannabis.
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		+	== Biochemistry ==
		+	CBN acts as a weak agonist of [[CB1 receptors]] but has a higher affinity to [[CB2 receptors]], with lower affinities in comparison to THC.
		+	[http://upload.wikimedia.org/wikipedia/commons/8/8d/Cannabinol-C4.png]
		+
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		+	== Medicinal Properties ==
		+	Because it is a somewhat selective CB2 receptor agonist, it is used experimentally as an immunosuppressant, which can be useful in autoimmune related diseases such as lupus and type 2 diabetes.
		+	CBN is the cannabinoid with very promising antibacterial properties that may prove useful in treating drug resistant bacterial infections [http://www.ncbi.nlm.nih.gov/pubmed/18681481].
		+	It has also been implicated as a bone stimulant, and may help regenerate bone mass lost due to osteoporosis.