Difference between revisions of "L-759,633"

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(Created page with "L-759,656 is an analgesic drug that is a cannabinoid agonist. It is a highly selective agonist for the CB2 receptor, with selectivity of 414x for CB2 over CB1,alth...")
 
 
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L-759,656 is an analgesic drug that is a [[cannabinoid]] agonist. It is a highly selective agonist for the [[CB2 receptor]], with selectivity of 414x for CB2 over [[CB1]],although it is still not as selective as newer agents such as [[HU-308]].
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L-759,633 is an analgesic drug that is a [[cannabinoid]] agonist. It is a fairly selective agonist for the [[CB2 receptor]], with selectivity of 163x for CB2 over [[CB1]].
 
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It produces some similar effects to other cannabinoid agonists such as analgesia, but with little or no sedative or psychoactive effects due to its weak CB1 activity, and a relatively strong antiinflammatory effect due to its strong activity at CB2.
 
It produces some similar effects to other cannabinoid agonists such as analgesia, but with little or no sedative or psychoactive effects due to its weak CB1 activity, and a relatively strong antiinflammatory effect due to its strong activity at CB2.
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==See also==
 
==See also==
  
* [[L-759,633]]
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* [[L-759,656]]
  
 
* [[L-768,242]]
 
* [[L-768,242]]

Latest revision as of 07:38, 16 February 2015

L-759,633 is an analgesic drug that is a cannabinoid agonist. It is a fairly selective agonist for the CB2 receptor, with selectivity of 163x for CB2 over CB1.

It produces some similar effects to other cannabinoid agonists such as analgesia, but with little or no sedative or psychoactive effects due to its weak CB1 activity, and a relatively strong antiinflammatory effect due to its strong activity at CB2.

See also