# Difference between revisions of "O-1871"

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(Created page with "'''O-1871''' is a potent cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan in 2002. It has a CB1 receptor affinity of 2.0nM and a CB2 receptor...") |
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− | '''O-1871''' is a potent [[cannabinoid]] agonist which was invented by Billy R Martin and Raj K Razdan in 2002. It has a [[CB1 | + | '''O-1871''' is a potent [[cannabinoid]] agonist which was invented by Billy R Martin and Raj K Razdan in 2002. It has a [[CB1]] receptor affinity of 2.0nM and a CB2 receptor affinity of 0.3nM. Structurally, O-1871 is a cyclohexylphenol derivative related to [[CP 47,497]], and so is illegal in most jurisdictions where CP 47,497 and its derivatives are banned. However the 3,3-dimethylcyclohexyl substituent of O-1871 can be replaced by various other groups, producing other potent compounds such as the cycloheptyl derivative O-1656 and the 2-adamantyl derivative O-1660, as well as the corresponding 3,5-dichlorophenyl derivative, which are not cyclohexylphenol derivatives. |

## Latest revision as of 04:06, 14 April 2015

**O-1871** is a potent cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan in 2002. It has a CB1 receptor affinity of 2.0nM and a CB2 receptor affinity of 0.3nM. Structurally, O-1871 is a cyclohexylphenol derivative related to CP 47,497, and so is illegal in most jurisdictions where CP 47,497 and its derivatives are banned. However the 3,3-dimethylcyclohexyl substituent of O-1871 can be replaced by various other groups, producing other potent compounds such as the cycloheptyl derivative O-1656 and the 2-adamantyl derivative O-1660, as well as the corresponding 3,5-dichlorophenyl derivative, which are not cyclohexylphenol derivatives.