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5F-PB-22 or Quinolin-8-yl 1-pentyfluoro-1H-indole-3-8-carboxylate is a designer drug and a possible cannabinoid agonist. The structure of 5F-PB-22 appears to have been designed with an understanding of structure-activity relationships within the indole class of cannabinoids on the Forendex website of potential drugs of abuse.

In January 2014, 5F-PB-22 was designated as a Schedule I controlled substance in the United States.

See also